As "giant snakes on the loose" films go 2004's Boa Vs Python is surprisingly decent. An entrepeneur and big game hunter stages a hunt, his latest quarry an 80 foot long python. The python escapes into an underground public water works facility. The government agent assigned to the case relies on a herpetologist and his own gargantuan snake, a 70 foot long scarlet colored boa to track down the python so that it can be disposed of. Predictably, the two leviathan snakes battle it out at the conclusion of the film.
The trailer:
